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Front Pharmacol 11:356 Grnewald A, Kumar KR, Sue CM (2019) New insights into the complex role of mitochondria in Parkinsons disease

Important note: Vitamin B12 injection therapy usually begins with a "loading phase." A common regimen involves daily injections of 1000 micrograms (mcg) for one week, followed by weekly injections for one month

2 The native hormone has a serious pharmaceutical liability: it is prone to aggregation into amyloid fibrils and has a plasma half-life measured in minutes, which is why the first amylin-based drug, pramlintide, had to be injected before every major meal

Asti E, Lovece A, Bonavina L, et al

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