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ROS includes molecules such as superoxide anion (O 2 ), hydrogen peroxide (H 2 O 2 ), singlet oxygen ( 1 O 2 ), and hydroxyl radicals (OH), 101,102 which can impair mitochondrial function by damaging mtDNA, proteins, membrane lipids, and other cellular components

[DOI] [PMC free article] [PubMed] [Google Scholar] 117.Ladang A., Beaudart C., Reginster J.Y., Al-Daghri N., Bruyre O., Burlet N., Cesari M., Cherubini A., da Silva M.C., Cooper C., et al

Zhu TJ, Chen YD, Qian MB, Zhu HH, Huang JL, Zhou CH, Zhou XN

345 Nevertheless, it should be noted that not all malignant breast cells express MTs, implying the presence of alternative mechanisms to prevent zinc cytotoxicity